95. Antibody-based imaging of bioreductive prodrug release in hypoxia Ç. Tosun, M. Mallerman, A. L. D. Wallabregue, S. Phillips, C. M. Edwards, S. J. Conway, E. M. Hammond. ChemRxiv, 2023, DOI: 10.26434/chemrxiv-2023-9n5s0

94. Two color imaging of different hypoxia levels in cancer cells A. Wallabregue, H. Bolland, S. Faulkner, E. M. Hammond, S. J. Conway. J. Am. Chem. Soc., 2023, 145, 2572

93. Identification of histone peptide binding specificity and small molecule ligands for the bromodomains of TRIM33α and TRIM33β A. R. Sekirnik, J. K. Reynolds, L. See, J. P. Bluck, A. R. Scorah, C. Tallant, B. Lee, K. B. Leszczynska, R. L. Grimley, R. I. Storer, M. Malattia, S. Crespillo, S. Caria, S. Duclos, E. M. Hammond, S. Knapp, G. M. Morris, F. Duarte, P. C. Biggin, S. J. Conway. ACS Chem.Biol., 2022, 17, 2753

92. Increasing Diversity in Admissions to Postgraduate Study. S. J. Conway, A. Kawamura, T. M. Marr, F. Platt, A. J. Russell. J. Med. Chem., 2022, 65, 5867.

91. Welcome to ACS Bio & Med Chem Au. S. J. Booker, S. J. Conway, A. Lavasavifar. ACS Bio & Med Chem Au, 2021, 1, 1.

90. Zap-Pano: a photocaged pro-drug of the KDAC inhibitor panobinostat. K. S. Troelsen, E. D. D. Calder, A. Skwarska, E. M. Hammond, S. J. Conway. ChemMedChem, 2021, 16, 3691

89. Celebrating the Medicinal Chemistry of Gunda Georg and Shaomeng Wang. M. L. Bolognesi and S. J. Conway. J. Med. Chem., 2021, 64, 17541

88. Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. M. Brand, J. Clayton, M. Moroglu, M. Schiedel, S. Picaud, J. P. Bluck, A. Skwarska, A. K. N. Chan, C. M. C. Laurin, A. R. Scorah, K. F. L. See, T. P. C. Rooney, O. Fedorov, G. Perell, W. A. Cortopassi, K. E. Christensen, R. I. Cooper, R. S. Paton, W. C. K. Pomerantz, P. C. Biggin, E. M. Hammond, P. Filippakopoulos, S. J. Conway. J. Med. Chem., 2021, 64, 10102

87. Simplifying the submissions requirements for the Journal of Medicinal Chemistry. C. W. Lindsley, J. Barrow, K. Chibale, M. L. Bolognesi, S. J. Conway, W. Denny, K. Ding, S. Laufer, L. Lai, H. Liu, N. Neamati, T. Suzuki, N. Meanwell, W. Young. J. Med. Chem., 2021, 64, 7877

86. Bioactivation of isoxazole-containing bromodomain and extra terminal domain (BET) inhibitors. N. R. Flynn, M. D. Ward, M. A. Schleiff, C. M. C. Laurin, S. J. Conway, G. Boysen, S. J. Swamidass, G. P. Miller. Metabolites, 2021, 11, 390

85. Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor. A. Skwarska, E. D. D. Calder, I. N. Mistry, D. Sneddon, S. J. Conway, E. M. Hammond. Cell Chem Biol., 2021, 28, 1258.

84. Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications N. Favalli, G. Bassi, C. Pellegrino, J. Millul, R. De Luca, S. Cazzamalli, S. Yang, A. Trenner, N. Mozzafari, R. Myburgh, M. Moroglu, S. J. Conway, A. Sartori, M. M. Manz, R. A. Lerner, P. Vogt, J. Scheuermann, D. Neri. Nature Chem., 2021, 13, 540

83. Novel bioactivation of isoxazole-containing bromodomain and extra terminal domain (BET) inhibitors. G. P. Miller, M. Schleiff, N. Flynn, M. Ward, C. Laurin, S. J. Conway, S. Swamidass. FASEB J., 2021, 35, DOI: 10.1096/fasebj.2021.35.S1.04681.

82. Development of isotope-enriched phosphatidylinositol-4- and 5-phosphate cellular mass spectrometry probes A. M. Joffrin, A. M. Saunders, D. Barneda, V. Flemington, A. L. Thompson, H. J. Sanganee, S. J. Conway. Chemical Science, 2021, 12, 2549.

81. Fragment-based identification of ligands for bromodomain-containing factor 3 of Trypanosoma cruzi. C. M. C. Laurin, J. P. Bluck, A. K. Chan, M. Keller, A. Boczek, L. E. Jennings, A. R. Scorah, K. F. L. See, D. S. Hewings, F. Woodhouse, J. K. Reynolds, M. Schiedel, P. G.Humphreys, P. C. Biggin, S. J. Conway. ACS Infect. Diseases, 2020, 7, 2238.

80. Epigenetics 2.0: Special Issue on Epigenetics – Call for Papers. S. J. Conway, P. Arimondo, C. Arrowsmith, J. Jin, C. Luo, N. Meanwell, W. Young, G. Georg, S. Wang. J. Med. Chem., 2020, 63, 12129-12130.

79. Pharmacological inhibition of ATR can block autophagy through an ATR-independent mechanism E. Bowler, A. Skwarska, J. D. Wilson, S. Ramachandran, H. Bolland, A. Easton, M-S.Hwang, K. B. Leszczynska, S. J. Conway, E. M. Hammond. iScience, 2020, 101668

78. A single-stranded DNA-encoded chemical library based on a stereoisomeric scaffold enables ligand discovery by modular assembly of building blocks. G. Bassi, N. Favalli, M. Vuk, M. Catalano, A. Martinelli, A. Trenner, A. Porro, S. Yang, C L. Tham, M. Moroglu, W. W. Yue, S. J. Conway, P. K. Vogt, A. A. Sartori, J. Scheuermann, D. Neri. Advanced Science, 2020, 2001970

77. Selective fragments for the CREBBP bromodomain identified from an Encoded Self‑Assembly Chemical Library. M. Catalano, M. Moroglu, P. Balbi, F. Mazzieri, J. Clayton, K.H. Andrews, M. Bigatti, J. Scheuermann, S. J. Conway, D. Neri. ChemMedChem, 2020, 15, 1752-1756

76. Hypoxia-activated pro-drugs of the KDAC inhibitor vorinostat (SAHA). E. D. D. Calder, A. Skwarska, I. N. Mistry, D. Sneddon, S. J. Conway, E. M. Hammond. Tetrahedron, 2020, 76, 131170 (Invited submission in honour of Prof. Steve Davis)

75. Bifunctional molecules beyond PROTACs. S. J. Conway. J. Med. Chem., 2020, 63, 2802-2806

74. PPIs as therapeutic targets for anticancer drug discovery: the case study of MDM2 and BET bromodomain inhibitors. M. Espadinha, S. J. Conway, M. M. M. Santos. Small Molecule Drug Discovery; A. Trabocchi, E. Lenci Eds.; 2020, 267–288.

73. Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria. B. A. Geddes, P. Paramasivan, A. M. Joffrin, K. Grant, A. L. Thompson, K. E. Christensen, S. J. Conway, G. E. D. Oldroyd, P. S. Poole. Nature Communications, 2019, 10, 3430.

72. Interaction of the mechanosensitive channel, MscS, with the membrane bilayer through lipid intercalation into grooves and pockets. T. Rasmussen, A. Rasmussen, L. Yang, C. Kaul, S. Black, H. Galbiati, S. J. Conway, S. Miller, P. Blount, I. R. Booth. J. Mol. Biol., 2019, 431, 3339.

71. Chemical epigenetics: the impact of chemical and chemical biology techniques on bromodomain target validation. M. Schiedel, M. Moroglu, D. M. H. Ascough, A. E. R. Chamberlain, J. J. A. G. Kamps, A. R. Sekirnik, S. J. Conway. Angew. Chem. Int. Ed., 2019, 58, 8353-8357.

70. Hypoxia-activated, small-molecule-induced gene expression. S. L. Collins, J. Saha, L. C. Bouchez, E. M. Hammond, S. J. Conway. ACS Chem. Biol., 2018, 13, 3354-3360.

69. Small molecules as tools to study the chemical epigenetics of lysine acetylation. M. Schiedel and S. J. Conway. Curr. Opin. Chem. Biol., 2018, 45, 166.

68. BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability. L. E. Jennings, M. Schiedel, D. S. Hewings, S. Picaud, C. M. C. Laurin, P. A. Bruno, J. P. Bluck, A. R. Scorah, L. See, J. K. Reynolds, M. Moroglu, I. N. Mistry, A. Hicks, P. Guzanov, J. Clayton, C. N. G. Evans, G. Stazi, P. C. Biggin, A. K. Mapp, E. M. Hammond, P. G. Humphreys, P. Filippakopoulos, S. J. Conway. Bioorg. Med. Chem., 2018, 26, 2937.

67. High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions J. O. Phillips, L. E. Butt, C. A. Henderson, M. Devonshire, J. Healy, S. J. Conway, N. Locker, A. R. Pickford, H. A. Vincent, A. J. Callaghan. Nucleic Acids Res., 2018, 46, e86

66. Adenosine Monophosphate binding stabilizes the KTN domain of the Shewanella denitrificans Kef potassium efflux system. C. Pliotas, S. C. Grayer, S. Ekkerman, A. K. N. Chan, J. Healy, P. Marius, W. Bartlett, A. Khan, W. A. Cortopassi, S. A. Chandler, T. Rasmussen, J. L. P. Benesch, R. S. Paton, T. D. W. Claridge, S. Miller, I. R. Booth, J. H. Naismith, S. J. Conway. Biochemistry, 2017, 56, 4219.

65. Clinical advances of hypoxia-activated prodrugs in combination with radiation therapy. I. N. Mistry, M. Thomas, E. D. Calder, S. J. Conway, E. M. Hammond. Int. J. Radiation Oncol. Biol. Phys., 2017, 98, 1183.

64. CYP450 Enzymes effect oxygen-dependent reduction of azide-based fluorogenic dyes. L. J. O’Connor, L. K. Folkes, G. Brown, S. J. Conway, E. M. Hammond. ACS Central Science, 2017, 3, 20.

63. Pyocyanin degradation by a tautomerizing demethylase inhibits Pseudomonas aeruginosa biofilms. K. C. Costa, N. R. Glasser, S. J. Conway, D. K. Newman. Science, 2017, 355, 170.

62. Editorial overview: Chemical genetics and epigenetics. D. G. Fujimori and S. J. Conway. Curr. Opin. Chem. Biol., 2016, 33, 6.

61. Isoxazole-derived amino acids are bromodomain-binding acetyl-lysine mimics: incorporation into histone H4 peptides and histone H3. A. R. Sekirnik (née Measures), D. S. Hewings, N. H. Theodoulou, L. Jursins, K. Lewendon, L. E. Jennings, T. P. C. Rooney, T. D. Heightman, S. J. Conway. Angew. Chem. Int. Ed., 2016, 55, 8353.

60. Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs. L. J. O’Connor, C. Cazares-Körner, J. Saha, C. N. G. Evans, M. R. L. Stratford, E. M. Hammond, S. J. Conway. Nature Protocols, 2016, 11, 781.

59. The photochemical thiol-ene reaction as a versatile method for the synthesis of glutathione S-conjugates targeting the bacterial potassium efflux system Kef. J. Healy, T. Rasmussen, S. Miller, I. R. Booth, S. J. Conway. Org. Chem. Front., 2016, 3, 439.

58. Epigenetics: Novel therapeutics targeting epigenetics. S. J. Conway, P. M. Woster, W. J. Greenlee, G. Georg, S. Wang. J. Med. Chem., 2016, 59, 1247.

57. Efficient synthesis of 2-nitroimidazole derivatives and the bioreductive clinical candidate Evofosfamide (TH-302). L. J. O’Connor, C. Cazares-Körner, J. Saha, C. N. G. Evans, M. R. L. Stratford, E. M. Hammond, S. J. Conway. Org. Chem. Front., 2015, 2, 1026.

56. Emerging Epigenetic Therapies – Bromodomain ligands. In Epigenetic Cancer Therapy. D. S. Hewings, T. P. C. Rooney, S. J. Conway. S. Gray Ed.; Elsevier: Amsterdam, 2015; pp 495.

55. Quantitative hopanoid analysis enables robust pattern detection and comparison between laboratories. C-W. Wu, L. Kong, M. Bialecka-Fornal, S. Park, A. L. Thompson, G. Kulkarni, S. J. Conway, D. K. Newman. Geobiology, 2015, 13, 391.

54. Small molecule inhibitors of bromodomain-acetyl-lysine interactions. M. Brand, A. Measures, B. Wilson, W. A. Cortopassi, R. Alexander, M. Höss, T. P. C. Rooney, D. S. Hewings, R. Paton, S. J. Conway. ACS Chem. Biol., 2015, 10, 22.

53. Epigenetics: Novel therapeutics targeting epigenetics. S. J. Conway, P. M. Woster, J.-K. Shen, G. Georg, S. Wang. J. Med. Chem., 2015, 58, 523.

52. Synthesis of highly water-soluble adamantyl phosphoinositide derivatives. M. Gregory, M-X. Yin, M. McConville, E. Williams, A. N. Bullock, S. J. Conway, A. B. Holmes. Aust. J. Chem., 2015, 68, 543.

51. Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains. D. A. Hay, O. Fedorov, S. Martin, C. Wells, S. Picaud, M. Philpott, O. P. Moteiro, C. M. Rogers, S. J. Conway, T. P. C. Rooney, A. Tumber, C. Yapp, P. Filippakopoulos, M. E. Bunnage, S. Müller, S. Knapp, C. J. Schofield, P. E. Brennan. J. Am. Chem. Soc., 2014, 136, 9308.

50. A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation–π interaction. T. P. C. Rooney, P. Filippakopoulos, O. Fedorov, S. Picaud, D. A. Hay, S. Martin, A. Tumber, C. M. Rogers, M. Philpott, M. Wang, A. L. Thompson, T. D. Heightman, D. C. Pryde, A. Cook, R. S. Paton, S. Müller, S. Knapp, P. E. Brennan, S. J. Conway. Angew. Chem. Int. Ed., 2014, 53, 6126.

49. Understanding the structural requirements for activators of the Kef bacterial potassium efflux system. J. Healy, S. Ekkerman, C. Pliotas, M. Richard, W. Bartlett, S. C. Grayer, G. Morris, S. Miller, I. R. Booth, S. J. Conway, T. Rasmussen. Biochemistry, 2014, 53, 1982.

48. Phenotypic screening and fragment-based approaches to the discovery of small-molecule bromodomain ligands. L. E. Jennings, A. R. Measures, B. G. Wilson, S. J. Conway. Future Med. Chem., 2014, 6, 179.

47. CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A. A. C. Cazares-Körner, I. M. Pires, I. D. Swallow, S. C. Grayer, L. J. O’Connor, M. M. Olcina, M. Christlieb, S. J. Conway, E. M. Hammond. ACS Chem. Biol., 2013, 8, 1451.

46. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. D. S. Hewings, O. Fedorov, P. Filippakopoulos, S. Martin, S. Picaud, A. Tumber, C. Wells, M. M. Olcina, K. Freeman, A. Gill, A. J. Ritchie, D. W. Sheppard, A. J. Russell, E. M. Hammond, S. Knapp, P. E. Brennan, S. J. Conway. J. Med. Chem., 2013, 56, 3217.

45. Reflections on stereochemistry. S. J. Conway. Nature Chem., 2013, 5, 86.

44. The design and synthesis of 5- and 6- isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains. D. Hay, O. Fedorov, P. Filippakopoulos, S. Martin, M. Philpott, D. S. Hewings, S. Uttakar, T. D. Heightman, S. J. Conway, S. Knapp, P. E. Brennan. Med. Chem. Commun., 2013, 4, 140.

43. NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing. L. C. Davis, A. J. Morgan, J-. L. Chen, C. Snead, D. Bloor-Young, M. N. Stanton-Humphreys, S. J. Conway, E. Shenderov, G. C. Churchill, J. Parrington, V. Cerundolo, A. Galione. Curr. Biol., 2012, 22, 2331.

42. Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions. D. S. Hewings, T. P. C. Rooney, L. E. Jennings, D. Hay, C. J. Schofield, P. E. Brennan, S. Knapp, S. J. Conway.† J. Med. Chem., 2012, 55, 9393.

41. Bromodomains: are readers right for epigenetic therapy? S. J. Conway. ACS Med. Chem. Lett., 2012, 3, 691.

40. The use of phosphate bioisosteres in medicinal chemistry and chemical biology.T. S. Elliott, A. Slowey, Y. Ye, S. J. Conway. Med. Chem. Commun., 2012, 3, 735.

39. Wavelength-orthogonal photolysis of neurotransmitters in vitro. M. N. Stanton-Humphreys, R. D. T. Taylor, C. McDougall, M. L. Hart, C. T. A. Brown, N. J. Emptage, S. J. Conway. Chem. Commun., 2012, 48, 657.

38. 3,5-Dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands. D. S. Hewings, M. Wang, M. Philpott, O. Fedorov, P. Filippakopoulos, S. Picaud, C. Vuppusetty, B. Marsden, S. Knapp, S. J. Conway, T. D. Heightman, J. Med. Chem., 2011, 54, 6761. (Highlighted in Faculty 1000, recognised as highly cited by J. Med. Chem.).

37. KefF, regulatory subunit of the potassium efflux system KefC, shows quinone oxidoreductase activity. L. Lyngberg, J. Healy, W. Bartlett, S. Miller, S. J. Conway, I. R. Booth, T. Rasmussen. J. Bacteriol., 2011, 193, 4925.

36. Mitochondrial beta-amyloid in Alzheimer’s disease. E. Borger, K. E. A. Muirhead, Z. Allen, J. A. Ainge, S. J. Conway, F. J. Gunn-Moore, Biochem. Soc. Trans., 2011, 39, 868.

35. Development of inositol-based antagonists for the D-myo-inositol 1,4,5-trisphosphate receptor. N. S. Keddie, Y. Ye, T. Aslam, T. Luyten, D. Bello, C. Garnham, G. Bulynck, A. Galione, S. J. Conway. Chem. Commun., 2011, 47, 242.

34. (-)-CHANA, a fluorogenic probe for detecting amyloid binding alcohol dehydrogenase HSD10 activity in living cells. K. E. A. Muirhead, M. Froemming, X. Li, K. Musilek, S. J. Conway, D. Sames, F. J. Gunn-Moore. ACS Chem. Biol., 2010, 5, 1105.

33. Mechanism of ligand-gated potassium efflux in bacterial pathogens. T. P. Roosild, S. Castronovo, J. Healy, S. Miller, C. Pliotas, T. Rasmussen, W. Bartlett, S. J. Conway and I. R. Booth. Proc. Natl. Acad. Sci. USA, 2010, 107, 19784.

32. The consequences of mitochondrial amyloid beta peptide in Alzheimer’s disease. K. E. A. Muirhead, E. Borger, L. Aitken, S. J. Conway and F. J. Gunn-Moore. Biochem. J., 2010, 426, 255.

31. Synthesis and biological evaluation of phosphatidylinositol phosphate affinity probes. S. J. Conway, J. Gardiner, S. J. A. Grove, M. K. Johns, Z.-Y. Lim, G. F. Painter, D. E. J. E. Robinson, C. Schieber, J. W. Thuring, L. S.-M. Wong, M.-X. Yin, A. W. Burgess, B. Catimel, P. T. Hawkins, N. T. Ktistakis, L. R. Stephens and A. B. Holmes. Org. Biomol. Chem., 2010, 8, 66.

30. A synthesis of dioctanoyl phosphatidylinositol. T. S. Elliott, J. Nemeth, S. A. Swain and S. J. Conway. Tetrahedron: Asymmetry, 2009, 20, 2809.

29. Synthesis of the marine glycolipid dioctadecanoyl discoside. G. J. Florence, T. Aslam, G. J. Miller, G. D. S. Milne and S. J. Conway. Synlett, 2009, 3099.

28. Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. M. P. Van Ryssen, N. Avlonitis, R. Giniatulin, C. McDougall, J. L. Carr, M. N. Stanton-Humphreys, C. T. A. Brown, L. Khiroug and S. J. Conway. Org. Biomol. Chem., 2009, 7, 4695.

27. Synthesis and biological evaluation of a novel cardiolipin affinity matrix. M. K. Johns, M. Yin, S. J. Conway, D. E. J. E. Robinson, L. M.-M. Wong, R. Bamert, R. E. H. Wettenhall and A. B. Holmes, Org. Biomol. Chem., 2009, 7, 3691.

26. Increased InsP3Rs in the junctional sarcoplasmic reticulum augment Ca2+ transients and arrhythmias associated with cardiac hypertrophy. D. Harzheim, M. Movassagh, R. S.-Y. Foo, R. Oliver, T. Aslam, S. J. Conway, M. D. Bootman and H. L. Roderick, Proc. Natl. Acad. Sci. USA, 2009, 106, 11406.

25. A type 2 Ferrier rearrangement-based synthesis of D-myo-inositol 1,4,5-trisphosphate. N. S. Keddie, G. Bultynck, T. Luyten, A. M. Z. Slawin and S. J. Conway. Tetrahedron: Asymmetry, 2009, 20, 857. (Invited submission for Prof. George Fleet’s 65th birthday issue).

24. Caged AG10: new tools for spatially predefined mitochondrial uncoupling. N. Avlonitis, S. Chalmers, C. McDougall, M. N. Stanton-Humphreys, C. T. A. Brown, J. G. McCarron and S. J. Conway. Mol. BioSyst., 2009, 5, 450. (Highlighted in RSC Chemical Biology and Faculty of 1000).

23. TRPing the switch on pain: an introduction to the chemistry and biology of capsaicin and TRPV1. S. J. Conway. Chem. Soc. Rev., 2008, 37, 1530.

22. Facile one-pot synthesis of 5-substituted hydantoins. R. G. Murray, D. Whitehead, F. Le Strat and S. J. Conway. Org. Biomol. Chem., 2008, 6, 988. (Highlighted in SYNFACTS).

21. Purinergic receptor-stimulated IP3-mediated Ca2+ release enhances neuroprotection by increasing astrocyte mitochondrial metabolism during ageing. J. Wu, J. D. Holstein, G. Upadhyay, D.-T. Lin, S. J. Conway, E. Muller, J. D. Lechleiter. J. Neurosci., 2007, 27, 6510.

20. Temporal changes in atrial EC-coupling during prolonged stimulation with endothelin-1. M. D. Bootman, D. Harzheim, L. Smyrnias, S. J. Conway and H. L. Roderick. Cell Calcium, 2007, 42, 489.

19. The proapoptotic factors Bax and Bak regulate T cell proliferation through control of endoplasmic reticulum Ca2+ homeostasis. R. G. Jones, T. Bui, C. White, M. Madesh, C. M. Krawczyk, T. Lindsten, B. J. Hawkins, S. Kubek, K. A. Frauwirth, Y. L. Wang, S. J. Conway, H. L. Roderick, M. D. Bootman, H. Shen, J. K. Foskett and C. B. Thompson. Immunity, 2007, 27, 268.

18. Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives. S. J. Conway and G. J. Miller, . Nat. Prod. Rep., 2007, 24, 687.

17. Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate. D. Bello, T. Aslam, G. Bultynck, A. M. Z. Slawin, H. L. Roderick,M. D. Bootman and S. J. Conway. J. Org. Chem., 2007, 72, 5647.

16. Defective chemattractant-induced calcium signalling in S100A9 null neutrophils. E. McNeill, S. J. Conway, H. L. Roderick, M. D. Bootman and N. Hogg. Cell Calcium, 2007, 41, 107.

15. The synthesis of membrane permeant derivatives of myo-inositol 1,4,5-trisphosphate. S. J. Conway, J. W. Thuring, S. Andreu, B. T. Kvinlaug, H. L. Roderick, M. D. Bootman and A. B. Holmes. Aust. J. Chem., 2006, 59, 887.

14. Inositol 1,4,5-trisphosphate supports the arrhythmogenic action of endothelin-1 on ventricular cardiac myocytes. A. Proven, H. L. Roderick, S. J. Conway, M. J. Berridge, J. K. Horton, S. J. Capper and M. D. Bootman. J. Cell Sci., 2006, 119, 3363.

13. In vitro photo-release of a TRPV1 agonist. J. L. Carr, K. N. Wease, M. P. Van Ryssen, S. Paterson, B. Agate, K. A. Gallagher, C. T. A. Brown, R. H. Scott and S. J. Conway. Bioorg. Med. Chem. Lett., 2006, 16, 208.

12. The spatial pattern of atrial cardiomyocyte calcium signalling modulates contraction. L. Mackenzie, H. L. Roderick, M. D. Bootman, M. J. Berridge, S. J. Conway, A. B. Holmes, and P. Lipp. J. Cell Sci., 2004, 117, 6327.

11. Inositol 1,4,5-trisphosphate receptors in the heart. L. Mackenzie, H. L. Roderick, A. Proven, S. J. Conway and M. D. Bootman. Biol. Res., 2004, 37, 553.

10. Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. R. Chen, I. Valencia, F. Zhong, K. S. McColl, H. L. Roderick, M. D. Bootman, M. J. Berridge, S. J. Conway, A. B. Holmes, G. A. Mignery, P. Velez and C. W. Distelhorst. J. Cell. Biol., 2004, 166, 179.

9. Production and characterization of reduced NAADP (nicotinic acid-adenine dinucleotide phosphate). R. A. Billington, J. W. Thuring, S. J. Conway, L. Packman, A. B. Holmes, and A. A. Genazzani. Biochem. J., 2004, 378, 275.

8. Regulation of InsP(3) receptor activity by neuronal Ca2+- binding proteins. N. N. Kasri, A. M. Holmes, G. Bultynck, J. B. Parys, M. D. Bootman, K. Rietdorf, L. Missiaen, F. McDonald, H. De Smedt, S. J. Conway, A. B. Holmes, M. J. Berridge, and H. L. Roderick. EMBO J., 2004, 23, 312.

7. Co-incident signalling between μ-opioid and M3 muscarinic receptors at the level of Ca2+ release from intracellular stores: lack of evidence for Ins(1,4,5)P3 receptor sensitization. D. S. K. Samways, W. H. Li, S. J. Conway, A. B. Holmes, M. D. Bootman, and G. Henderson. Biochem. J., 2003, 375, 713.

6. Tetrabenzyl pyrophosphate. T. D. Nelson, J. D. Rosen, M. Bhupathy, J. McNamara, M. J. Sowa, C. Rush, and L. S. Crocker; Checked by S. J. Conway, and A. B. Holmes, Org. Synth., 2003, 80, 219.

5. Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals. J. C. Miller, P. A. Howson, S. J. Conway, R. V. Williams, B. P. Clark, and D. E. Jane. Brit. J. Pharmacol., 2003, 139, 1523.

4. 2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels. C. M. Peppiatt, T. J. Collins, L. Mackenzie, S. J. Conway, A. B. Holmes, M. D. Bootman, M. J. Berridge, J. T. Seo, and H. L. Roderick. Cell Calcium, 2003, 34, 97.

3. Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4. S. J. Conway, J. C. Miller, A. D. Bond, B. P. Clark, and D. E. Jane. J. Chem. Soc., Perkin Trans. 1, 2002, 1625.

2. Distinct intracellular calcium transients in neurites and somata integrate neuronal signals. F. W. Johenning, M. Zochowski, S. J. Conway, A. B. Holmes, P. Koulen, and B. E. Ehrlich. J. Neurosci., 2002, 22, 5344-5353.

1. Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors. S. J. Conway, J. C. Miller, P. A. Howson, B. P. Clark, and D. E. Jane. Bioorg. Med. Chem. Lett., 2001, 11, 777.